Retinoids are medications that are Vitamin A derived such as Retin-A, Renova, Tazorac and others.  The Retinoids have been assumed to be the best anti-aging product.  The benefits are increased cell turnover to soften and smoothen wrinkles, stimulate collagen production and fade sunspots.  However now there are reports that Retinoids can cause thinning of the skin as well as chronic irritation and inflammation which can result in premature aging. Repeated and excessive inflammation of the skin will increase collagen breakdown which in turn increases appearance of lines, wrinkles and sagging.

According to some dermatologists applying more than recommended pea-sized amount of the product can result in excessive flaking of the skin and possibly skin irritation.   Applying too much or using them too often should be avoided to prevent or decrease chance of irritation and inflammation.